HEOR Services

Get Evidence That Speaks To Decision Makers

Alkemi’s HEOR services transform clinical data into actionable evidence that drives faster adoption, global readiness, and measurable business impact.

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Published in Value in Health

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Top 5% Presenter At ISPOR

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80+ HEOR Publications

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I was incredibly pleased with the engagement and the rich insights shared.

Evidence Matters More Than Ever

HEOR is more than publishing models. Today, evidence must meet HTA standards, persuade payers, achieve reimbursement, keep pace with launch timelines, and a changing landscape. Here’s how Alkemi helps you find and implement the right approach.

  • Studies built for health technology assessments

  • Proof that persuades healthcare decision makers

  • Evidence designed for real-world challenges

Read Our Case Studies

You Deserve Proof That Speaks To Every Stakeholder

Evidence Systems Designed For Real-World Challenges

Alkemi’s two HEOR systems tackle the challenges teams face most: one anticipates risks early in trial design, the other responds fast when pricing or coverage pressure threatens adoption. Both deliver credible, decision-ready evidence that turns data into value.

Evidence Packages Made Practical

With Alkemi, you don’t get research for research’s sake. You get evidence packages built to answer the questions payers, regulators, and clinicians will ask. Every deliverable is practical, clear, and ready to use the moment you need it.

Pre-Launch Deliverables

Before launch, we help you build the evidence foundation: from mapping the landscape to designing studies and creating tools that prepare your team for every conversation.

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Landscape Assessments

Evaluate current data, treatment patterns, and other factors shaping health economics and outcomes research in your market.

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Primary Insights

Structured payer, clinician, and KOL interviews that guide HEOR research priorities—so your studies focus on the outcomes and factors decision makers care about most.

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Trial Data Collection Plan

Design clinical trials to capture the health outcomes, safety, and economic impact metrics that regulators and government agencies expect.

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Evidence Gaps Analysis

Assess where your current HEOR studies fall short, and identify the resources needed to strengthen your value story.

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Evidence Generation Plan

A roadmap for outcomes research, comparative effectiveness, economic analysis models, and real-world evidence that shows how treatments work in practice.

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Global Market & HTA Plan

Translate your HEOR data into submission-ready formats that meet diverse payer and HTA requirements across countries, supporting adoption and long-term commercial success.

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Value Communications (GVD, AMCP, Payer)

Turn HEOR studies into global value dossiers, AMCP dossiers, and payer tools that clearly communicate product value across healthcare systems and decision makers.

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Engagement Plans (Payer, Guidelines, KOL)

Apply HEOR evidence to shape the conversation—ensuring your research resonates with payers, value analysis panels, guideline committees, and key opinion leaders.

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Field Training Tools

Equip internal teams with resources to communicate HEOR evidence consistently across every job function.

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Mock Negotiations

Simulate payer and HTA discussions using your HEOR data and models to stress-test arguments before real negotiations.

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Access Navigator

A structured framework for applying HEOR insights to navigate payer requirements, guideline expectations, and policy environments with confidence.

Post-Launch Deliverables

Once your treatment is on the market, we extend your evidence strategy. So you can continuously adapt to competition, generate new insights, and prove long-term value.

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Advisory Boards (US & EU)

Gather structured insights from payers, clinicians, and policy experts to refine HEOR strategies and strengthen evidence over time.

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Competitive Response Plans

Leverage HEOR studies and real-world evidence to counter competitor claims, address new drug launches, defend pricing, and protect your market position.

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Value Positioning Updates

Continuously adapt your value story as new HEOR data and RWE emerge, keeping your product differentiated and relevant to decision makers and healthcare systems.

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RWE Strategy & Development

Develop real-world evidence programs that demonstrate how treatments work in practice, improve patient care, and support ongoing commercial success.

Access The Alkemi Advantage

We make evidence work for you. These are the features and benefits that help you translate data into decisions that accelerate adoption and sustain long-term value.

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Evidence That’s Relevant, Right Now

Move faster with analyses that use current clinical data, real-world evidence, and pragmatic endpoints so decision makers see immediate value.


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Rare Disease Expertise

From small patient populations to sparse trial data, we build credible models that persuade regulators, payers, and providers where skepticism is highest.


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Speed Without Sacrifice

We design cost-effectiveness analyses and outcomes research that satisfy HTA rigor while matching commercial launch timelines. Within 90 days, we deliver evidence syntheses, gap analyses, and early models that teams can use immediately.


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Commercial Alignment

Our HEOR outputs tie directly to strategy: pricing justification, payer negotiations, guideline adoption, and long-term market positioning.


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A Path To Achieve Reimbursement

We build the HEOR evidence payers and HTA require - budget impact models, cost-effectiveness analyses, real-world data, and value frameworks that secure reimbursement and expand patient access.


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Global Perspective

Dossiers, models, and value frameworks that meet the diverse requirements of HTA bodies across US, Canada, EU4, UK, Nordics, and beyond.


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Highlight Unmet Needs

Identify gaps in patient quality, public health outcomes, and treatment patterns—showing why your drug or device is indispensable in today’s healthcare systems.


Built on Rigor. Proven in Practice.

Our work has been published in Value in Health, recognized among the top 5% of presenters at ISPOR, and used to secure NCCN guideline inclusion within days of launch. But the real test of HEOR isn’t earning a spot in a journal.

It’s whether your evidence shapes adoption and reimbursement decisions.

At Alkemi, every study, model, and value framework we deliver is built to hold up under the toughest scrutiny, whether that’s an HTA review, a payer negotiation, or a regulatory discussion.

More importantly, we give our clients the confidence that their value story will stand up in front of any stakeholder.

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With Alkemi, you get evidence packages that payers, clinicians, and agencies can understand, trust, and act on.

Testimonials

"When I presented the project output to our leadership, they said: 'You took a really scary situation and broke it down in terms we understand. It sounds like the team has a clear plan going forward'."

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Sr. Director, Outcomes Research, RWE & Epi
Mid-sized Biotech Company

“I wanted to reach out and tell you that the SLR publication is getting GREAT reception from senior BU leadership across the company. Thank you again for your and Alkemi’s support on this project!”

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Associate Director, HEOR Center of Excellence
Major Medical Device Company

"There was such interest [among our team] following the readout, that we're planning to schedule another session with an even broader group to review the findings. We would love for you to be part of that discussion to provide additional color and answer any questions."

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Associate Director of Innovation, Global Medical Affairs
Major Medical Device Company

Thanks for sharing the final materials! Many thanks to you and the rest of the Alkemi team for a success project. We really appreciated the excellent collaboration and quality work. It’s been a pleasure working with all of you on this project! Looking forward to the next one…

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Sr. Director, HTA, Value & Evidence
Major Pharmaceutical Company

Testimonials

“Really appreciate your support - as you know I rang you in a bit of a panic a few weeks ago, yet the session came across as though you’d been working on it for months.”

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Associate Director
Major Medical Device Company

“When I presented the project output to our leadership, they said: 'You took a really scary situation and broke it down in terms we understand. It sounds like the team has a clear plan going forward'. That was my goal for this project so sounds like we achieved it.”

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Head of Medical Affairs
Rare Disease Immunology Biotech

“In a record 3.5 days, guidelines have been updated to include [treatment]. Woohoo!!”


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Vice President, HEOR
Rare Disease Oncology (Breakthrough)

We Stand Behind Our Work

In HEOR, the only thing worse than weak data is wasted time.

That’s why every Alkemi project comes with our commitment: if the deliverable doesn’t stand up to stakeholder scrutiny, we’ll refine it until it does.

You’ll always walk away with evidence you can trust.

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Turn Data Into Evidence That Changes Decisions

Start building an evidence package that accelerates adoption, secures reimbursement, and drives long-term value. Schedule a strategy call with an HEOR Expert today.

Frequently Asked Questions

What makes Alkemi’s HEOR work different from other firms?
Can you support rare disease or small patient populations?
How do you handle uncertainty when evidence is incomplete?
Do you only focus on publications and models?
Will this be too academic and slow?
What if our evidence isn’t perfect yet? Shouldn’t we wait for stronger data?
How do you ensure HEOR projects tie back to business impact?
We already have an internal HEOR team. Why would we need Alkemi?
Can a boutique firm really handle our complex global needs?
Do you build capability or create dependency?