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Market Access

Payer Value Testing to Inform U.S. Market Access Strategy

image of pharmacy community engagement activities
Client Profile

Large Pharmaceutical

Key Stakeholders

HTA, Value & Evidence, Global Access Strategy & Pricing

Asset

Phase III

Disease Area

Dermatology

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Client Profile

Large Pharmaceutical

Key Stakeholders

HTA, Value & Evidence, Global Access Strategy & Pricing

Asset

Phase III

Disease Area

Dermatology

Situation

The client was developing a systemic therapy with Phase III trials underway.

Payers were expected to question whether the condition represented a true medical need, creating a challenging access and pricing environment.

The client engaged Alkemi to identify effective ways to convey unmet need, demonstrate value, and inform U.S. market access and pricing strategy.

Approach

1. Conducted secondary research to assess the disease landscape and identify relevant analogues to inform payer discussion.

2. Designed payer advisory materials, including value narratives, clinical logic, and discussion guides structured to elicit decision-relevant feedback.

3. Moderated a payer advisory board with U.S. payers, KOLs, and clinical experts to test assumptions and capture insights on access and pricing expectations.

The focus throughout:

Use payer input early to shape strategy rather than react to it later.

Deliverables

1
Scoping Literature Review to assess evidence, map aspirational value messages and develop questions for advisory board meeting.
2
Full-day Payer Advisory Board Meeting to solicit feedback on perceptions of value and pricing and to inform strategies for evidence generation.
3
Summary report synthesizing payer feedback and strategic implications for pricing and access.
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Impact

"Thanks to the whole team involved in staging this Advisory Council. I was fortunate to be able to attend and here the insights from the council members firsthand. The report provides an excellent summary." - VP, Global Access Strategy and Pricing Lead

Clearer Access Expectations:

Payer feedback clarified how unmet need and value would be evaluated, reducing uncertainty around coverage and pricing.

Stronger Value Positioning:

Insights were used to refine how the therapy’s value was framed in payer discussions.

Improved Access Readiness:

Early testing helped the client enter later-stage planning with greater confidence in access and pricing strategy.

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