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Payer Value Story and Field Toolkit to Accelerate Adoption in Rare Cardiology

image of pharmacy community engagement activities
Client Profile

Mid-size Biopharmaceutical

Key Stakeholders

HEOR, Market Access

Asset

Launched

Disease Area

Rare Cardiovascular Disease

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Client Profile

Mid-size Biopharmaceutical

Key Stakeholders

HEOR, Market Access

Asset

Launched

Disease Area

Rare Cardiovascular Disease

Situation

A mid-size biopharmaceutical company had reached a major regulatory milestone for a novel cardiovascular therapy.

Despite strong clinical differentiation, early payer discussions raised a concern: U.S. uptake could stall without a clear, payer-relevant value narrative.

The client engaged Alkemi to validate the most compelling value drivers, refine a differentiated U.S. payer story, and equip teams with tools to support adoption in a rapidly evolving market.

Approach

1. Reviewed global value propositions, U.S. value assessments, and competitive dynamics to identify gaps in payer-relevant claims.

2. Conducted payer, IDN decision-maker, and clinician interviews to prioritize and pressure-test clinical and economic value drivers.

3. Developed a U.S. payer value story grounded in evidence and aligned to payer decision-making needs.

4. Translated the narrative into field-ready tools and trained cross-functional teams to support consistent execution.

The focus throughout:

Make differentiation land with U.S. payers and make it usable in the field.

Deliverables

1
Rapid insight review and competitive scan validating U.S. burden, treatment patterns, and relevant value drivers.
2
Stakeholder interviews to validate and prioritize payer value drivers.
3
U.S. payer value story articulating the most relevant clinical and economic impacts.
4
Field-based communication toolkit to support payer-facing discussions.
5
6

Impact

“Following our recent payer discussions, I wanted to share how impactful Alkemi’s work has been. The work made a noticeable difference in how our story landed.” - Senior Market Access Lead

Stronger Payer Conversations:

Teams were equipped with a validated, U.S.-specific narrative grounded in evidence.

Improved Differentiation:

The value story strengthened positioning in a crowded and evolving market.

Greater Internal Alignment:

Cross-functional teams aligned on messaging and execution to support adoption.

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