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Market Access

Payer and Guideline Strategy to Accelerate Adoption at Rare Oncology Launch

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Client Profile

Mid-size Biopharmaceutical

Key Stakeholders

Market Access, HEOR, Medical Affairs

Asset

Phase III

Disease Area

Oncology

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Client Profile

Mid-size Biopharmaceutical

Key Stakeholders

Market Access, HEOR, Medical Affairs

Asset

Phase III

Disease Area

Oncology

Situation

A mid-size biopharmaceutical company was 18 months from launching a therapy for a rare oncologic disease with no prior approved treatments.

To minimize time to coverage following FDA approval, the team needed to clearly position clinical value with both payers and national guideline committees.

The client engaged Alkemi to develop a payer dossier and a parallel guideline strategy to support rapid post-approval adoption.

Approach

1. Conducted targeted analyses to position trial and subgroup data for both payer and guideline audiences.

2. Synthesized literature and clinical data into a differentiated value narrative formatted for AMCP submission.

3. Developed guideline positioning tools and supporting materials for use in NCCN and other compendia discussions.

4. Built a submission roadmap and tracker to support efficient follow-up and process management.

The focus throughout:

Align payer and guideline strategy before approval to shorten time to adoption.

Deliverables

1
AMCP dossier articulating clinical and value evidence to payers.
2
Evidence prioritization and guideline positioning communication tool for clinical decision-makers.
3
Roadmap and tracker to manage submissions, follow-up, and milestone progress.
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Impact

“Not only were they knowledgeable of guideline processes, but also internal dynamics that can delay launch. Very impressive.” - Global Market Access Lead

Rapid Payer Readiness:

AMCP dossier approved for distribution within two days of FDA approval.

Accelerated Guideline Inclusion:

A favorable NCCN guideline update advocating for use of the therapy was issued within 10 days of approval.

Broader Clinical Recognition:

Additional clinical compendia issued positive recommendations following communication efforts.

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