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HTA

HTA Launch Readiness for a Systemic Dermatology Therapy

image of pharmacy community engagement activities
Client Profile

Large Pharmaceutical

Key Stakeholders

HTA, Value & Evidence, Global Access Strategy & Pricing

Asset

Phase III

Disease Area

Dermatology

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Client Profile

Large Pharmaceutical

Key Stakeholders

HTA, Value & Evidence, Global Access Strategy & Pricing

Asset

Phase III

Disease Area

Dermatology

Situation

The client was preparing to bring a systemic therapy for a dermatologic condition into HTA-driven markets.

While clinical data supported approval, reimbursement decisions would depend on how disease burden, long-term value, and uncertainty were interpreted by HTA bodies.

Early signals from affiliates suggested misalignment across markets; differences in burden framing, economic assumptions, and anticipated objections that could surface late and slow access.

The client engaged Alkemi to identify likely HTA challenges early and bring markets into alignment before launch.

Approach

1. Established a core working team across Value & Evidence and Market Access to align on objectives and success criteria.

2. Conducted structured interviews with country affiliates to understand local reimbursement pathways, current treatment costs, and anticipated HTA challenges.

3. Designed and led a full-day hybrid strategy workshop focused on identifying access risks and evaluating mitigation options across markets.

4. Synthesized insights into clear strategic outputs and country-level tools to support ongoing HTA planning and execution.

The focus throughout:

Identify where access risk would emerge and address it early.

Deliverables

1
Pre-workshop interviews with 10 country affiliates to assess local reimbursement pathways, current treatments and costs, expected HTA challenges, and evidence gaps.
2
Full-day hybrid strategy workshop to align on access risks and mitigation approaches.
3
Workshop summary report synthesizing insights and recommended actions.
4
Country-level HTA strategy trackers to monitor landscape changes and mitigation progress.
5
6

Impact

"Thanks for sharing the final materials! Many thanks to you and the rest of the Alkemi team for a success project. We really appreciated the excellent collaboration and quality work. It’s been a pleasure working with all of you on this project! Looking forward to the next one…" - Senior Director, Global HTA, Value & Evidence Strategy

Early Local Launch Readiness:

Affiliates gained clarity on anticipated HTA challenges and how global strategy supported local access planning.

Sharper Investment Decisions:

The team prioritized evidence, modeling refinements, and communication support tied to reimbursement risk.

Reduced Reimbursement Risk:

Early alignment across markets lowered the likelihood of late-stage access delays and improved confidence in pricing and access discussions.

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