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HEOR

Evidence Generation Program to Establish Burden and Market Need in Rare Oncology

image of pharmacy community engagement activities
Client Profile

Mid-size Biopharmaceutical

Key Stakeholders

Market Access, HEOR, Medical Affairs

Asset

Phase III

Disease Area

Oncology

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Client Profile

Mid-size Biopharmaceutical

Key Stakeholders

Market Access, HEOR, Medical Affairs

Asset

Phase III

Disease Area

Oncology

Situation

A mid-size biopharmaceutical company was 18 months from launching a therapy for a rare oncologic disease with no prior approved treatments.

To support payer discussions and market adoption, the team needed credible, published evidence demonstrating disease burden, unmet need, and real-world impact.

The client engaged Alkemi to design and execute a coordinated evidence generation strategy to define market need and strengthen launch readiness.

Approach

1. Leveraged large claims datasets to quantify economic burden and healthcare utilization in the United States.

2. Designed and published national patient and provider preference studies to document burden, care patterns, and unmet need.

3. Developed a targeted patient engagement and recruitment strategy to support participation in real-world evidence studies.

The focus throughout:

Build publishable, payer-relevant evidence before launch.

Deliverables

1
U.S. burden of disease claims study quantifying economic impact and resource utilization.
2
National patient and provider preference studies documenting disease burden and treatment journey.
3
Patient engagement and recruitment strategy to support real-world evidence enrollment.
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Impact

"We appreciate you helping us keep a complex, multi-author program efficient and on schedule." - Medical Affairs Lead

High-Impact Publications:

Patient and provider preference studies were published in Cancer and ranked among the top 10% most downloaded articles in the year of launch.

Stronger Payer Discussions:

Published burden and preference data supported payer communications and value articulation.

Broad Coverage Achieved:

Evidence contributed to securing coverage across major commercial and public U.S. payers.

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